open-label, randomised clinical trial

Code file 1: bumetanide.R

Lingli Zhang, et al. Qiang Luo*, et al., Barbara J Sahakian, Ching-Po Lin*, Fei Li*. Symptom improvement in children with autism spectrum disorder following bumetanide administration is associated with decreased GABA/glutamate ratios. Translational Psychiatry 10, Article number: 9 (2020)

double-blind, randomised, placebo-controlled trial

Code file 2: doubleblindplacebocontrolRCT.R

Yuan Dai, et al., Barbara J Sahakian, Qiang Luo*, Fei Li*. Bumetanide treatment in young children with autism spectrum disorder reduces disease severity and improves social cognition and motor behaviour: a randomised, double-blind, placebo-controlled trial. 2020. (under preparation)