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Update index.md
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kendomaniac authored Oct 18, 2023
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Expand Up @@ -88,7 +88,7 @@ We have done a 10XGenomics scRNAseq experiment including the following elements:

<img border="0" src="../../images/drivers_minimal_relations.jpg" width="500px">

The above figure described the driver genes associated to each cell line. Only a minimal part of the connections has been shown to easy readability of the image. Full list of the interactions depicted by [*IPA*](https://digitalinsights.qiagen.com/products-overview/discovery-insights-portfolio/analysis-and-visualization/qiagen-ipa/?utm_source=QDI_GA_IPA&cmpid=QDI_GA_IPA&gclid=CjwKCAjwpuajBhBpEiwA_Ztfha6eGDCSYCgWJdU_WLaESr4az3OOXllkow2o0Xmfxz8OhFo7Z2cpxhoC4okQAvD_BwE) are available at figshare [10.6084/m9.figshare.23284748 (This doi is not active, yet)]. All driver genes have been observed in resistence occuring upon treatment with [*Isomertinib*](https://en.wikipedia.org/wiki/Osimertinib) of EGFR mutated lung cancers [[*Gomatou et al. (2023)*](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913144/)].
The above figure described the driver genes associated to each cell line. Only a minimal part of the connections has been shown to easy readability of the image. Full list of the interactions depicted by [*IPA*](https://digitalinsights.qiagen.com/products-overview/discovery-insights-portfolio/analysis-and-visualization/qiagen-ipa/?utm_source=QDI_GA_IPA&cmpid=QDI_GA_IPA&gclid=CjwKCAjwpuajBhBpEiwA_Ztfha6eGDCSYCgWJdU_WLaESr4az3OOXllkow2o0Xmfxz8OhFo7Z2cpxhoC4okQAvD_BwE) are available at figshare [[*10.6084/m9.figshare.23284748*](https://doi.org/10.6084/m9.figshare.23284748.v1)]. All driver genes have been observed in resistence occuring upon treatment with [*Isomertinib*](https://en.wikipedia.org/wiki/Osimertinib) of EGFR mutated lung cancers [[*Gomatou et al. (2023)*](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9913144/)].

The experiment was done using CellPlex technology from 10XGenomics allowing multiplexing samples into a single channel and therefore removing unwanted batch effects.

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