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Cell Models for TOPAS/Geant4 and the inclusion of nano particles in particle scattering simulations. The C++ classes in this repository extend the functionality of the TOPAS (http://www.topasmc.org/) MC program, which is itself a wrapper of the Geant4 MCS Toolkit (http://geant4.org).

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TOPAS-CellModels

  1. Description:

Cell Models for TOPAS/Geant4 and the inclusion of nano particles in particle scattering simulations.

The C++ classes in this repository extend the functionality of the TOPAS (http://www.topasmc.org/) Monte-Carlo program, which is itself a wrapper of the Geant4 MCS Toolkit (http://geant4.org).

  1. Installation:

Installation:

Navigate to the TOPAS extension directory:

cd ~/topas_extensions/

Clone or download the sourcecode into your TOPAS extension directory:

git clone https://github.com/BAMresearch/TOPAS-CellModels.git

Change to your topas directory:

cd ~/Topas/

Install it:

cmake ./ -DTOPAS_EXTENSIONS_DIR=~/topas_extensions/TOPAS-CellModels && make -j4

  1. Description:

A simple spherical cell with nanoparticles can be generated in a fast manner. The user has the option to include nanoparticles and different organelles in the cell, e.g. a nucleus, mitochondria, a cell membrane. Details can be found in https://doi.org/10.1038/s41598-021-85964-2

  1. Usage:

Examples can be found in the "examples/" directory.

  1. Bugs:

Please report bugs to [email protected] or on https://github.com/BAMresearch/TOPAS-CellModels

  1. Literature:

If you use this extension please cite the following literature:

Hahn, M.B., Zutta Villate, J.M. "Combined cell and nanoparticle models for TOPAS to study radiation dose enhancement in cell organelles." Sci Rep 11, 6721 (2021).

https://doi.org/10.1038/s41598-021-85964-2

  1. Etc:

Tags: topas topasmc topasmcs topas-mc topas-mcs topas-nbio mcs geant4 geant4-dna

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Cell Models for TOPAS/Geant4 and the inclusion of nano particles in particle scattering simulations. The C++ classes in this repository extend the functionality of the TOPAS (http://www.topasmc.org/) MC program, which is itself a wrapper of the Geant4 MCS Toolkit (http://geant4.org).

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