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queries.graphql
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queries.graphql
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query test {
expression: target(ensemblId: "ENSG00000091831") {
id
approvedSymbol
proteinAnnotations {
id
accessions
functions
pathways
similarities
subcellularLocations
subunits
}
expressions {
tissue {
id
label
anatomicalSystems
organs
}
rna {
zscore
value
unit
level
}
protein {
reliability
level
cellType {
reliability
name
level
}
}
}
knownDrugs {
rows {
drugType
targetId
diseaseId
}
}
}
search(queryString: "erectile") {
total
aggregations {
total
entities {
total
name
categories {
name
total
}
}
}
hits {
id
entity
category
score
object {
... on Target {
approvedSymbol
}
... on Drug {
name
}
... on Disease {
name
}
}
}
}
target(ensemblId: "ENSG00000138735") {
id
approvedSymbol
approvedName
bioType
hgncId
nameSynonyms
symbolSynonyms
tep {
uri
name
}
genomicLocation {
chromosome
start
end
strand
}
proteinAnnotations {
id
accessions
functions
}
geneOntology {
id
project
term
evidence {
id
label
}
}
safety {
adverseEffects {
activationEffects {
acuteDosing {
code
mappedTerm
termInPaper
}
general {
code
mappedTerm
termInPaper
}
}
}
safetyRiskInfo {
organsSystemsAffected {
code
mappedTerm
termInPaper
}
references {
pubmedId
refLabel
refLink
}
}
experimentalToxicity {
dataSource
dataSourceReferenceLink
experimentDetails {
assayFormatType
tissue
assayFormat
assayDescription
cellShortName
}
}
}
chemicalProbes {
probeminer
rows {
note
gene
}
}
hallmarks {
attributes {
name
reference {
pubmedId
description
}
}
}
tractability {
smallmolecule {
topCategory
}
antibody {
topCategory
}
}
knownDrugs {
uniqueDrugs
uniqueDiseases
uniqueTargets
count
}
cancerBiomarkers {
uniqueDrugs
uniqueDiseases
uniqueBiomarkers
count
}
relatedTargets {
maxCountAOrB
count
}
}
disease(efoId: "Orphanet_242") {
id
name
description
synonyms
therapeuticAreas {
id
name
}
parents {
name
}
children {
name
}
phenotypes {
url
name
disease
}
knownDrugs {
uniqueDrugs
uniqueDiseases
uniqueTargets
count
rows {
drugType
targetId
}
}
relatedDiseases {
maxCountAOrB
count
}
}
drug(chemblId: "CHEMBL192") {
id
name
synonyms
tradeNames
yearOfFirstApproval
drugType
maximumClinicalTrialPhase
hasBeenWithdrawn
withdrawnNotice {
classes
countries
reasons
year
}
internalCompound
mechanismsOfAction {
uniqueActionTypes
uniqueTargetTypes
rows {
mechanismOfAction
targetName
references {
ids
source
urls
}
targets {
approvedSymbol
}
}
}
blackBoxWarning
indications {
count
rows {
maxPhaseForIndication
references {
ids
source
urls
}
disease {
name
}
}
}
adverseEvents {
count
critVal
rows {
name
count
llr
criticalValue
}
}
knownDrugs {
uniqueDrugs
uniqueDiseases
uniqueTargets
count
rows {
drugType
targetId
diseaseId
phase
mechanismOfAction
status
activity
targetClass
ctIds
}
}
}
knwonDrugs: target(ensemblId: "ENSG00000105650") {
approvedSymbol
knownDrugs(sortField:"label", sortOrder:Asc) {
count
rows {
drugType
targetId
diseaseId
approvedSymbol
label
prefName
mechanismOfAction
drug {
synonyms
}
}
}
}
}