diff --git a/requirements.txt b/requirements.txt
index 59c8bdb..24d0624 100644
--- a/requirements.txt
+++ b/requirements.txt
@@ -1,5 +1,5 @@
 biopython==1.73
-numpy==1.16.2
+numpy==1.22.0
 pandas==0.24.2
 PyYAML==5.4
 tqdm==4.60.0
\ No newline at end of file
diff --git a/setup.py b/setup.py
old mode 100755
new mode 100644
index 7cb50bc..9e1c1ff
--- a/setup.py
+++ b/setup.py
@@ -26,7 +26,7 @@
     # installation info and requirements
     install_requires=[
         "biopython==1.73",
-        "numpy==1.16.2",
+        "numpy==1.22.0",
         "pandas==0.24.2",
         "PyYAML==5.4",
         "tqdm",