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Isotropic French-Wilson scaling uses grid points to efficiently estimate the resolution-dependent average intensity. However, anisotropic scaling currently does not. It just computes the full kernel matrix one row at a time. I see no reason why this couldn't use a grid like the isotropic version which would help combat overfitting and improve performance.
The text was updated successfully, but these errors were encountered:
Observation: in my use of this procedure in VALDO, I get better final results (difference map peak heights) for the isotropic scaling approach than for the anisotropic approach. It is also ~3-4x faster.
Isotropic French-Wilson scaling uses grid points to efficiently estimate the resolution-dependent average intensity. However, anisotropic scaling currently does not. It just computes the full kernel matrix one row at a time. I see no reason why this couldn't use a grid like the isotropic version which would help combat overfitting and improve performance.
The text was updated successfully, but these errors were encountered: