Running FitHiChIP error for .hic data

[cauyrd]

Hello, I have a .hic (h3k27ac HiChIP) data and a .bed.gz (H3k27ac peaks) downloaded from GEO and run FitHiChIP below:

./FitHiChIP_HiCPro.sh -C configfile_BiasCorrection_CoverageBias

Then I got errors below:

================ Processing input .hic file : /home/FitHiChIP/TestData/GSM5229037_VCaP_DMSO_4h_H3K27Ac.hic =================

Input - InpHiCFile : /home/FitHiChIP/TestData/GSM5229037_VCaP_DMSO_4h_H3K27Ac.hic
Input - OutFile : /home/FitHiChIP/TestData/results/Matrix_BinSize5000/VCaP_DMSO.interactions.initial_temp.bed
Input - TARGETRES : 5000
genomeID : hg38
[2500000, 1000000, 500000, 250000, 100000, 50000, 25000, 10000, 5000, 1000]
processing chromosome : ALL
Error finding block data
../FitHiChIP_HiCPro.sh: line 1185: 31124 Floating point exception(core dumped) $PythonExec ./src/Process_contactMat_HiC.py --hicfile ${InpHiCFile} --outfile ${Interaction_Initial_File_temp} --chromsizefile ${ChrSizeFile} --resolution ${BIN_SIZE}

Any suggestions why I got this error? You can find the GEO accession number based on the file name: GSM5229037 (.hic) and GSM5228990 (.bed.gz)

[ay-lab]

Hi @cauyrd
Could you please edit the line 52 of the script "src/Process_contactMat_HiC.py" by the following line?
if chrom.name != "All" or chrom.name != "ALL":

Let me know if it works. I'll then update the release.

[danidigi]

Hi all,
I have the same error when running FitHiChIP using my .hic file as input. Did your change work?
Thanks