Philosopher crashes with large pep.xml

[BernhardRetzl]

Hello, I tried to search against a large Database (TREMBL). I don´t know if Fraqpipe can be used for this? I somehow managed to make it run until the step where Philosopher is called. The file (interact-KN3RS_RA4_1_2360.pep.xml) is large (900MB) and philosopher crashes. Do you have any suggestions how I can solve the or a better approach?

Sincerely, Bernhard

C:\Users\Proteomics\Downloads\fragpipe21.1\tools\philosopher_v5.1.0_windows_amd64\philosopher.exe filter --sequential --prot 0.01 --tag rev_ --pepxml D:\Data\Bernhard\Fraqpipe\results --protxml D:\Data\Bernhard\Fraqpipe\results\combined.prot.xml --razor
←[36mINFO←[0m[14:22:05] Executing Filter v5.1.0
←[36mINFO←[0m[14:22:05] Processing peptide identification files
←[36mINFO←[0m[14:22:05] Parsing D:\Data\Bernhard\Fraqpipe\results\interact-KN3RS_RA4_1_2360.pep.xml
←[31mERRO←[0m[14:22:14] Cannot read file. Error parsing the file
Process 'PhilosopherFilter' finished, exit code: 1
Process returned non-zero exit code, stopping