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README.md

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Classification of Streptococcus pyogenes strains by disease phenotypes and pathogenicity

  1. Create a profile HMM database specific to S. pyogenes. See README.md in doc/
  2. Compare profile HMM models using AUC scores. Create random forest classifiers using the top 10 models, where each classifier was built by labelling a disease phenotype as 1 and others as 0 at a time. See README.md in Jupyter/