Web server forwarding to DOH?

[Klaaktu]

Is there a way to forward DOH query from web server (nginx) to dnscrypt-proxy? I want to have DOH on the usual 443 port and /dns-query path, but a web server is already on the port.
Some stuff I found, will test them:

1. NGINX SSL Termination. Does DOH work in HTTP mode if no certificate is specified or URL is local host?
   EDIT: No, certificate and key are required. Though NGINX can connect the upstream server with HTTPS.
2. TCP & UDP forwarding. Is the DOH server in dnscrypt-proxy HTTP2, so only TCP forwarding is needed?
   EDIT: Stream forwarding doesn't seem to be able to do sub-path.
3. Use doh-server instead of the built-in. Seem to be able to be connected with HTTP.